Duromine and liver

How does Duromine affect liver? – This question worries many obese people. After all, a huge number of medications has a negative impact on the liver function. Many people treating obesity have problems with this organ.

Multiple clinical trials show that Duromine (Phentermine) can affect

Central nervous system

Gastrointestinal tract

Cardiovascular system

However, there has been established no connection between Duromine use and change in the liver functions.

Duromine capsules can be used in patients with mild, moderate, as well as severe liver diseases.

Some anti-obesity drugs, for example, liraglutide, should not be used with severe hepatic insufficiency.

Any anorexigenic drugs can affect the liver function. After all, they get into the blood and then into the brain. One of the liver functions is excretion of substances that should not be in the blood.

Duromine capsules contain an active substance Phentermine (phenyl tertiary butylamine, C10H15N), which suppresses appetite.

20-30% of Phentermine is metabolized in the liver and excreted in urine and feces.

70-80% of Phentermine is not metabolized and is excreted unchanged in the urine.

Use of a Duromine 15 mg, 30 mg or 40 mg capsule per day does not have a significant effect on the liver function. Negative effect on the liver may occur, but only in overdose.

Therefore, the daily Duromine dose must never exceed 40mg, regardless of the obesity severity. Even if a patient misses a dose of 40mg, he must never double the dose of this weight loss drug.

It is very important to refrain from alcohol drinks during Duromine therapy. Alcohol affects the liver functions and increases the drug toxic effect on it.

Duromine does its work; it effectively suppresses appetite. Anti-obesity drug in conjunction with healthier eating and increase in the overall level of physical activity helps stably lose weight, including in patients with hepatic diseases.

Duromine is not used to treat liver diseases, but it can be useful for improving the functions of this organ. After 12 weeks of using Duromine and weight reduction by 5-10%:

Duromine is not used to treat liver diseases, but it can be useful for improving the functions of this organ. After 12 weeks of using Duromine and weight reduction by 5-10%:

  • the amount of fat around and inside the liver decreases
  • risks of developing liver diseases significantly decrease

If the patient has already a liver disease and he uses medicines to treat it, he must consult the doctor and make sure that they do not interact with Duromine.

More than 50% of people with overweight or obesity have nonalcoholic fatty liver disease. The management of this disease is still in its infancy. Studies continue, but there are still no drugs used to treat this serious disease.

Stable weight loss is often the only therapeutic recommendation for most patients with nonalcoholic fatty liver disease. Duromine will help reduce the amount of fat in the liver, as well as in other organs and parts of the body.